Comparison of Sural Nerve Amplitude and Sural/Radial Amplitude Ratio in Electrodiagnosis of patients with neuropathy in Type 2 diabetes

Abstract

Diabetic neuropathy is the most common and bothersome diabetes mellitus complication, leading to considerable morbidity and mortality. The results of these studies and the importance of early detection and prevention of polyneuropathy in diabetic patients motivated the authors to carry out the present study. In this cross-sectional study all consecutive patients with type 2 diabetes mellitus were referred to the Endocrinology Clinic at Golestan Hospital in Ahvaz, Iran. The Nihon Kochden gadget was utilized on all patients, who were all examined by an individual. Average sensory amplitude was defined as greater than 6 V for the sural nerve and greater than 15 V for the radial nerve. In the present investigation, a sural/radial nerve amplitude ratio greater than or equal to 21 percent was considered normal. In total, 80 subjects were included in the analysis, there is a non-significant direct correlation between the sural nerve and sural/radial nerve amplitude ratio, to diagnose patients with and without neuropathy (p=0.625). Moreover, there is a non-significant direct correlation between the sural nerve and sural/radial nerve amplitude ratio with the body mass index of patients with diabetes, and this correlation is negligible (p>0.05). The findings demonstrated that sural/radial nerve amplitude ratio was a promising method for detecting neuropathy in patients with type 2 diabetes. Also, sural nerve and sural/radial nerve amplitude ratio had a significant inversion relationship with age and duration of diabetes for detecting diabetic neuropathy in type 2 diabetes patients.