Abstract
AIM: This research aim to know the comparison of efficacy of the effect therapy uses generic ciprofloxacin and branded drug tequinol from patient of typhoid fever.
 METHODS: The research method has the character of the descriptive observational with the technique intake of sample is consecutive sampling/quota sampling. Subject research was conducted on 67 sample fulfilling criterion of inclusion and exclusion diagnosed by typhoid fever at period January–March 2018.
 RESULTS: Thirty-four patients use the generic ciprofloxacin and 33 patients use the brand tequinol. Time of fever degradation for patient using brand tequinol range from 1 to 3 day and for patient using generic ciprofloxacin 3–7 day.
 CONCLUSION: After tested to use the Mann–Whitney test, there is difference having a meaning of hospitalization of to lodge briefer and free from fever quicker at brand tequinol than generic ciprofloxacin at patient of typhoid fever in RSUD Haji Makassar (p < 0.05).
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