Abstract
Linac‐based stereotactic radiosurgery (SRS) has been widely used for treating small intracranial lesions. This technique allows conforming the dose distribution to the planning target volume (PTV), providing a steep dose gradient with the surrounding normal tissues. This is realized through dedicated collimation systems. The present study aims to compare SRS plans with two collimating systems: the beam modulator (BM) of the Elekta Synergy linac and the DirexGroup micromultileaf collimator (μMLC). Seventeen patients (25 PTVs) were planned both with BM and μMLC (mounted on an Elekta Precise linac) using the Odyssey (PerMedics) treatment planning system (TPS). Plans were compared in terms of dose‐volume histograms (DVH), minimum dose to the PTV, conformity index (CI), and homogeneity index (HI), as defined by the TPS, and doses to relevant organs at risk (OAR). The mean difference between the μMLC and the BM plans in minimum PTV dose was 5.7%±4.2% in favor of the μMLC plans. No statistically significant difference was found between the distributions of the CI values for the two planning modalities (p=0.54), while the difference between the distributions of the HI values was statistically significant (p=0.018). For both BM and μMLC plans, no differences were observed in CI and HI, depending on lesion size and shape. The PTV homogeneity achieved by BM plans was 15.1%±6.8% compared to 10.4%±6.6% with μMLC. Higher maximum and mean doses to OAR were observed in the BM plans; however, for both plans, dose constraints were respected. The comparison between the two collimating systems showed no substantial differences in terms of PTV coverage or OAR sparing. The improvements obtained by using μMLC are relatively small, and both systems turned out to be adequate for SRS treatments.PACS numbers: 87.53.Ly, 87.55.dk, 87.56.nk
Highlights
Linac-based stereotactic radiosurgery (SRS) is extensively used for treating small intracranial lesions
Patients The latest seventeen patients treated with SRS for brain tumors at the Radiotherapy Department of the Florence University were planned both with the beam modulator (BM) of the Elekta Synergy linac and the μMLC mounted on the Elekta Precise linac, using the treatment planning system (TPS) Odyssey (PerMedics Inc., San Bernardino, CA, version 4.4 and 4.6), a system capable of managing a collimator with bidirectional leaf banks
In a group of 25 lesions treated with SRS, the comparison between the two collimating systems μMLC and BM showed no substantial differences in terms of planning target volume (PTV) coverage or organs at risk (OAR) sparing
Summary
Linac-based stereotactic radiosurgery (SRS) is extensively used for treating small intracranial lesions. One of the main advantages exploited by this technique is the ability to conform the dose distribution to the planning target volume (PTV), providing a steep dose gradient between the PTV and the surrounding normal tissues. This is realized through the use of dedicated collimation systems with small size leaves. Available micromultileaf collimators (μMLC) with narrow leaf widths are generally “add-on” devices for use on nondedicated linac units. About 200 patients have been treated for intracranial lesions using this device. The collimator needs to be manually fixed to the linac gantry prior to each usage, and it reduces the clearance around the patient, limiting the possible beam entrances
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