Abstract

Background: Pressurized intraperitoneal aerosol chemotherapy (PIPAC) has been introduced for palliative treatment of peritoneal cancer (PC) and is currently tested also in the neoadjuvant and prophylactic setting. The aim was therefore to compare safety and tolerance of staging laparoscopy with or without PIPAC.

Highlights

  • Pressurized intraperitoneal aerosol chemotherapy (PIPAC) has been introduced for palliative treatment of peritoneal cancer (PC) and is currently tested in the neoadjuvant and prophylactic setting

  • PIPAC procedures took a median of 35 min (IQR: 25-67) longer

  • Objective clinical response was reported in the palliative setting in 62–88% of patients with ovarian cancer, between 50% and 91% for gastric cancer and 71–86% for colorectal cancer [8]

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Summary

Background

Pressurized intraperitoneal aerosol chemotherapy (PIPAC) has been introduced for palliative treatment of peritoneal cancer (PC) and is currently tested in the neoadjuvant and prophylactic setting. The aim was to compare safety and tolerance of staging laparoscopy with or without PIPAC

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Discussion
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