Abstract
Comparison of Specific Inhalation Challenge Test Results in Occupational and Non- Occupational Asthma Patients: Is Monitoring Peak Expiratory Flow Rate Sufficient for Diagnosis?
Highlights
Occupational Asthma (OA) has become the second most common occupational lung disease after pneumoconiosis in the developing countries [1]
We detected underdiagnosed cases rates were higher with diagnosing OA with Peak Expiratory Flow Rate (PEFR) monitoring alone
Our study demonstrated that Low Molecular Weight (LMW) agents cause immunological OA, independently from agent type and duration of exposure
Summary
OA has become the second most common occupational lung disease after pneumoconiosis in the developing countries [1]. About 10-25% of adult-onset asthma cases are caused by occupational exposures [2]. More than 200 specific agents encountered at work can cause asthma [3]. It is recommended that occupational asthma should be suspected in every newly diagnosed adult asthma [4]. The most important step to diagnosing OA is to take a detailed occupational exposure history. It follows by tests that will determine the relationship between the agent and the disease. It is difficult to detect the exposure agent that is cause asthma and/or establish direct causal relationship between the suspected occupational exposure agent and asthma
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