Abstract
Background Viridans group streptococci (VGS) are commensal flora of the upper respiratory tract in humans and can cause serious infections, like infective endocarditis, septicemia, and meningitis. Accurate identification of VGS to the species level is difficult because they share many physiological characteristics. We report a study using sequencing of 16S ribosomal DNA (rDNA) gene and sodA gene to discriminate VGS up to species level.
Highlights
Viridans group streptococci (VGS) are commensal flora of the upper respiratory tract in humans and can cause serious infections, like infective endocarditis, septicemia, and meningitis
Comparison of sodA and 16S ribosomal DNA (rDNA) sequencing for accurate species-level identification of viridans group streptococci (VGS) isolated from patients with infective endocarditis
Identification of VGS upto species level is difficult using phenotypic characteristics alone. 16S rDNA sequence analysis was found to be less reliable than sodA sequencing for the identification of closely related species such as S. mitis and S. oralis
Summary
Viridans group streptococci (VGS) are commensal flora of the upper respiratory tract in humans and can cause serious infections, like infective endocarditis, septicemia, and meningitis. Comparison of sodA and 16S rDNA sequencing for accurate species-level identification of viridans group streptococci (VGS) isolated from patients with infective endocarditis From First International Science Symposium on HIV and Infectious Diseases (HIV SCIENCE 2012) Chennai, India. Background Viridans group streptococci (VGS) are commensal flora of the upper respiratory tract in humans and can cause serious infections, like infective endocarditis, septicemia, and meningitis.
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