COMPARISON OF SINGLE VERSUS DOUBLE DRAIN ON POSTOPERATIVE SEROMA FORMATION FOLLOWING MODIFIED RADICAL MASTECTOMY IN A TERTIARY CARE CENTRE IN NORTH INDIA

Abstract

INTRODUCTION: The usefulness of drains on seroma formation after surgery for breast cancer is the most investigated and most controversial topic of debate for the clinical researchers. Hence this study was conducted to compare single drain and double drain among women with breast cancer who underwent MRM in preventing seroma formation and also to determine the role of other predictors on the same. MATERIAL AND METHODS: A hospital based non-randomized controlled trial was conducted among 84 women (42 women each in single drain and double drain group respectively) with breast cancer who underwent modied radical mastectomy in the department of General Surgery, GSVM Medical College, Kanpur from January 2019 to October 2020. All women were followed up after insertion of either single or double drain following MRM for seroma formation. The mean age of the study RESULTS: participants was 46.4 (12.1) years. The incidence of seroma formation was found to be 26.2% (95% CI: 17.5%-37.1%). On logistic regression 2 analysis there was a signicant association for BMI > 25 kg/m , hypertension and lymph node status with seroma formation. However, there was no signicant association for age, Diabetes Mellitus and number of drains (p>0.05) in logistic regression analysis. CONCLUSION AND RECOMMENDATIONS: Single or double drain techniques are equally effective in reducing the seroma formation ad associated complications following modied radical mastectomy. Lymph node status, BMI and hypertension were found to inuence seroma formation in our study. Further research with a larger sample size at a multicentric level is needed to make our study results robust for better management of these patients.