Abstract
1. 1. A comparative study on primary and secondary stimulation of oviduct δ-aminolaevulinic acid dehydratase (ALAD) (EC 4.2.1.24) was carried out with oestradiol-17β and/or testosterone administration in immature female chickens during 15-day-primary stimulation, 20-day-withdrawal and 15-day-secondary stimulation periods. 2. 2. Compared with primary stimulation in oestrogenized birds, synthesis and degradation rates of oviduct ALAD molecule during secondary stimulation increased 3.4- and 1.8-fold respectively, resulting in a rapid induction of the enzyme. 3. 3. Specific activity of oviduct ALAD in oestradiol-plus-testosterone treated birds became significantly higher than that of oestradiol alone during secondary stimulation, ,whereas no significant changes were observed during primary stimulation.
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