Abstract

Objective: To compare recurrence of intranasal polyps treated with intranasal polypectomy versus steroid use. Study Settings and Duration: ENT department Nishtar hospital Multan from 24 th December 2017 to 23 June 2018. Study design: randomized controlled trial Material and methods: All 50 cases were divided in two groups M and S. Group M were given oral prednisone (30-60 mg) for 15-20 days in tapering regimen while patients in S group, intranasal polypectomy done. Information was collected through pre-designed Performa. Mean and standard deviation was calculated for quantitative variables such as age. Frequencies and percentages were calculated for qualitative variables such as gender and outcome variable i.e. recurrence. Chi-square test was applied to compare recurrence in both groups and P ≤ 0.05 was considered as significant. Results: The mean age of patients in group A was 34.49 ± 6.51years and in group B was 34.15 ± 6.97years. Male were 64.44% and 35.56% were females with ratio of 1.81:1. The mean duration of disease in group A was 5.81 ± 4.33 days and in group B was 5.75 ± 4.56 days. Recurrence rate in Group A (steroid group) was 57.78% while in Group B (intranasal polypectomy group) was 22.22% (p =0.001) Conclusion: Intranasal polypectomy is more effective in terms of non-recurrence of nasal polyps as compared to steroid use in the management of nasal polyps. Keywords: Nasal polyps, non-recurrence, medical treatment, polypectomy. DOI : 10.7176/JMPB/60-06 Publication date :October 31 st 2019

Highlights

  • Abnormal lesions which are resulted from different types of diseases mechanisms within intra nasal cavity arising from mucosal surface of the nasal cavity or one or more than one paranasal sinuses are termed as nasal polyps

  • Inclusion criteria was as follows; Signs and symptoms of nasal polyps or chronic rhinosinusitis requiring polypectomy, abnormalities on CT scan confirming the diagnosis of chronic rhinosinusitis or nasal polyps, patients aged 18 or older

  • Semi translucent edematous masses in nasal and paranasal cavities are known as nasal polyps which most commonly originate from the mucosa of middle turbinate, the sinuses and middle nasal meatus, and prolapsed into the nasal cavity

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Summary

Introduction

Abnormal lesions which are resulted from different types of diseases mechanisms within intra nasal cavity arising from mucosal surface of the nasal cavity or one or more than one paranasal sinuses are termed as nasal polyps. Nasal polyps are often found at the outflow tract of the sinuses[1]. Allergic fungal sinusitis or chronic sinusitis are prone the development of nasal polyps in their nasal cavity. A polyp by nature could any of the following; antral-choanal polyp, malignant or benign tumor or a massive benign polyp[2]. Patient present with the complaints of nasal obstruction, watery rhinorrhea, sneezing, itchy eyes, anosmia and headache.[3] On examination with nasal speculum or endoscope, smooth, grey, glossy lesions hanging from narrow stalk are seen. Diagnosis is confirmed by coronal CT scan with bone window.[4]

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