Abstract
Low Level Laser Therapy (LLLT) is one of the various interventions to accelerate the rate of Orthodontic Tooth Movement (OTM) in adolescent patients who are undergoing en-mass retraction after all first bicuspid extractions. To assess the efficacy of LLLT in increasing the rate of OTM. Setting and sample population: Institutional Department of Orthodontics and Dentofacial Orthopaedics. Participants, study design and methods: 65 Patients requiring all first premolar extractions were randomly allocated to three groups. Two groups (Comprising of passive self-ligating brackets and conventional brackets) were treated with LLLT and one group served as the control (conventional brackets). The allocation ratio was 1:1:1.32. Eligibility criteria: adolescent patients with sound and healthy permanent dentition with Little's Irregularity Index<5mm. rate of tooth movement in mm/month. Randomization and blinding: computer-generated random allocation sequence; only the data analyser was blinded by coding the digital models. Patients were reviewed once every month till the completion of space closure. data normality was checked using Shapiro-Wilks test and Q-Q Plot. Parametric tests were applied for the inferential statistics (ANCOVA) with Dunnett's t test being used for post hoc analysis. There was a statistically significant enhancement in the rate of OTM in the 2 experimental groups (0.68/0.67mm/month in the right and left side of the maxilla and 0.66/0.65mm/month in the right and left side of the mandible) when compared with the control group (0.48mm/month in the maxilla and 0.48mm/month in the mandible) (P<0.05), but when the 2 experimental groups were compared no difference was observed (P>0.05). No serious harms were reported. A significant increase in the rate of OTM was observed with the application of LLLT. No difference was observed in the rate of OTM when comparing different ligation methods treated with LLLT. National Trial Registry (CTRI No- CTRI/2018/04/013156). Protocol was not published before trial commencement.
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