Comparison of pregnancy results between intrauterine insemination and intracervical insemination

Abstract

Objective To compare the difference of outcomes between intrauterine insemination (IUI) and intracervical insemination (ICI) with donor’s semen. Methods In this retrospective study, 325 patients were treated with 548 cycles artificial insemination with donor semen (AID) during the period from January 2015 to August 2016 in assisted reproductive technology research unit of Fujian maternity and children health hospital of Fujian medical university. Totally 200 cases including 360 cycles of ICI, and 125 cases including 188 cycles of IUI were performed and their pregnancy outcome were compared respectively. Results The total pregnancy rates, the pregnancy rates of natural treatment cycle, the pregnancy rates of ovarian stimulation treatment cycle and miscarriage rates in ICI groups were 14.74%, 18.54%, 10.71%, 11.76% and in IUI groups were 28.49%, 32.04%, 23.68%, 5.88%, respectively. The comparative difference between the two groups was significant (P<0.05). Conclusion Insemination parts may be one of the key factors influencing the AID successful pregnancy, IUI may improve the pregnancy outcome of AID. Key words: Artificial insemination with donor semen (AID); Intrauterine insemination (IUI); Intracervical insemination (ICI); Pregnancy rate