Comparison of posterior capsule opacification development with 2 single-piece intraocular lens types

Abstract

To evaluate the differences in the incidence of posterior capsule opacification (PCO) and visual and optical performance between2 hydrophobic acrylic single-piece sharp-edged intraocular lenses (IOLs) over 3years. Department of Ophthalmology, Medical University of Vienna, Vienna, Austria. Prospective randomized case series. Patients with bilateral cataract were prospectively randomizedto receive an Eyecee One IOL (IOL A) or an Acrysof SN60WF IOL (IOL B) and were followed for 36months. The corrected distance visual acuity (CDVA) and IOL decentration and tilt were measured. The PCO was quantified by analysis of standardized retroillumination images. The study comprised 160 eyes of 80 patients. The PCO incidence was low for both IOLs at all follow-up visits. Three years postoperatively, the median objective PCO score was 1.4 (range 0 to 5.6) for IOL A and 1.5 (range 0 to 5.0) for IOL B (P=.67). The neodymium:YAG (Nd:YAG) capsulotomy rate 3years after surgery was 16.4% and 6.0% (P=.06), respectively. Visual acuity and contrast sensitivity outcomes were also comparable at all follow-up visits. Both IOLs showed good capsular bag performance and low PCO rates 3years after surgery. Both IOLs also showed comparable results for visual acuity, contrast sensitivity, decentration and tilt, PCO score, slitlamp examination, and Nd:YAG capsulotomy rates.