Abstract
Polycystic ovarian syndrome is a very common female endocrine; metabolic and reproductive disorder mainly affects females of reproductive age. It is multiple organ disorder affects 5 to 10 % female population. The world occurrence of PCOS is 105 million in the age ranges from 15 to 45. This metabolic dysfunction is closely related with obesity, hirsutism, acne and pregnancy complications. Around 5-10% of female population is affected, obese women are more prone to PCOS. Objective: To evaluate the comparison of polycystic ovaries between obese and non-obese females. Methods: A literature search was performed with the use of search engines. The following search engines provided the articles for this systematic review, PubMed, Medscape, NCBI, and Google Scholar. For article searching following keywords were used; Polycystic ovaries, obese and non-obese. Results: As literature reviewed of 30 articles and only 39 were included in this review, it is found that Mean age of all subjects was 24-35 year. Obese 20-29 year and non-obese 19-35 year. Hirsutism was observed mostly in obese patient of PCOs and not observed in non-obese. Incidence of Amenorrhea was higher in non-obese than obese patients. Acne was observed in all patients.Conclusion: It is concluded that there is a significant effect of obesity on clinical features of patients with PCOS.
Highlights
The de nition of polycystic ovarian syndrome (PCOS) is initially represented as oligo/amenorrhoea hirsutism, fat and enlarged ovaries with multiple cysts and thickened tunica' by Stein and Leventhal in 1935 [1]
Incidence of Amenorrhea was higher in non-obese than obese patients
As literature reviewed of 300 articles and only 39 were included in this review, it was found that mean age of all subjects was 24-35 years
Summary
The de nition of polycystic ovarian syndrome (PCOS) is initially represented as oligo/amenorrhoea hirsutism, fat and enlarged ovaries with multiple cysts and thickened tunica' by Stein and Leventhal in 1935 [1]. The Rotterdam criteria advocated the presence of ≥12 follicles measuring 2-9 mm in diameter and of volume ≥10cm for polycystic ovarian morphology This description is su cient to characterize the polycystic ovary [28].with the passage of time, ultrasound technology have made signi cant advancements, latest ultrasound technology has better resolution and smaller follicles are detectable [29]. These advancement prompted concerns revising the factors to outline polycystic female internal reproductive organ morphology. Ovarian volume assessed by 2D TVS, of more than 13 cm3is expected as PCO with a speci city and a sensitivity of 100 and 50%, respectively [30,31]
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