Comparison of peripherally inserted central catheters (PICCs) versus totally implantable venous-access ports in pediatric oncology patients, a single center study

Hong Zhang,Yanfang Li,Jinqiu Fu,Nannan Zhu,Jing Liu,Yumei Li

doi:10.1038/s41598-022-07584-8

Abstract

To compare the efficacy of peripherally inserted central catheters (PICCs) and totally implantable venous-access ports (TIVAPs) for chemotherapy of pediatric patients with malignant tumors. A total of 96 children with malignant tumors who received catheterization of PICCs or TIVAPs for chemotherapy from May 2020 to May 2021 in Department of Pediatric Oncology of Qilu Hospital of Shandong University were selected. Then, the pathological features of disease, the age of children, the indwelling time, the incidence of postoperative complications, and the satisfaction degree were compared between the two groups. The age of children in the TIVAP group was younger than that in the PICC group (P < 0.05). The indwelling time in the TIVAP group was 7.2 ± 2.757 months,which was significantly longer than 5.65 ± 2.058 months in the PICC group (P < 0.05). The incidence of postoperative complications in the TIVAP group without systemic or local infection was markedly lower than that in the PICC group (P < 0.05). The satisfaction degree of patients in the TIVAP group without unsatisfied was markedly higher than that in the PICC group (P < 0.05). TIVAPs may be the first choice for chemotherapy of children with malignant tumors.

Highlights

The incidence of childhood cancer has increased over the past few decades w orldwide[1–6]
Necessity of regular periodic blood s ampling[13]. This retrospective study aimed to compare the efficacy of peripherally inserted central catheters (PICCs) and totally implantable venous-access ports (TIVAPs) for chemotherapy of pediatric patients with malignant tumors
Childhood retrospective cohort: a case–control study of childhood cancers treated with PICCs or TIVAPs

Summary

Introduction

The incidence of childhood cancer has increased over the past few decades w orldwide[1–6]. Cancers, especially childhood cancers, are currently treated by chemotherapy, and a long-term venous access is essential for the children with malignant diseases. Central venous catheters (CVCs) reduce the stimulation to the vein and skin and improve injection of liquid medicines, which are usually used for patients receiving chemotherapeutic d rugs[8]. Both peripherally inserted central catheters (PICCs) and totally implantable venous-access ports (TIVAPs) are frequently used for chemotherapy of children with c ancer[9]. Necessity of regular periodic blood s ampling[13] This retrospective study aimed to compare the efficacy of PICCs and TIVAPs for chemotherapy of pediatric patients with malignant tumors

Methods

Results

Discussion

Conclusion