Comparison of Patients with Ventilator-Associated Pneumonia Developed in Two Different Intensive Care Units of a Tertiary Hospital

Abstract

Aim: Our purpose is to compare the characteristics and 30-day mortality of ventilator-associated
 pneumonia (VAP) patients that developed in two different intensive care units (ICUs) in a tertiary hospital.
 Material and Methods: Patients who were over the age of 18 who developed VAP in two different
 ICUs of our hospital over two years were included in the study. Acute Physiology and Chronic Health
 Assessment II (APACHE II), Sepsis-Related Organ Failure Assessment (SOFA), Glasgow Coma Score
 (GCS), Clinical Pulmonary Infection Score (CPIS), infection markers, and 30-day mortality of the
 patients were evaluated. Physical conditions of Group 1 and Group 2, hand hygiene rates in ICU, nurse
 education level, and hospitalization rate in intensive care units were compared.
 Results: A total of 104 patients, 48 being in Group 1 and 56 being in Group 2, were analyzed. There
 was no significant difference between the two groups with regards of GKS, SOFA and CPIS scores.
 Acinetobacter baumanni was the most common agent in both groups. The hospitalization rate was
 found to be significantly higher in Group 2. 30-day mortality was 45.8% in Group 1 and 48.2% in Group
 2. It was found that a one unit increase in the SOFA hospitalization period reduced the risk of 30-day
 mortality. It was determined that a one unit increase in the age ratio in Group 2 increased the risk of
 30-day mortality 1.085 times, and the increase in the mean SOFA score in all patients and Group 1
 decreased the length of the hospitalization period.
 Conclusion: We found a 30-day mortality rate of 47.1% in patients diagnosed with VAP. An increase in
 SOFA score increases the risk of 30-day mortality, while a prolonged hospitalization period decreases
 the risk of mortality.