Comparison of particulate matter emission and soluble matter collected from combustion cigarettes and heated tobacco products using a setup designed to simulate puffing regimes

Ana Amorós-Pérez,Laura Cano-Casanova,María Del Carmen Román-Martínez,María Ángeles Lillo-Ródenas

doi:10.1016/j.ceja.2021.100144

Ana Amorós-Pérez, Laura Cano-Casanova + Show 2 more

Open Access

https://doi.org/10.1016/j.ceja.2021.100144

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Abstract

An experimental setup was designed and optimized to collect particulate matter suspended in cigarettes smoke or in the aerosol generated during the use of heated tobacco products (HTPs). The setup is mainly based on a gas washing flask containing water where particulate matter and soluble compounds can be trapped, resembling interaction in the body. This system allows to perform puffing experiments in conditions similar to those of the Health Canada Intense puffing regime. In the study, cigarettes and Heets (in IQOS heater) from Philip Morris Products were used. Complementary characterization of this particulate matter has been extracted from experiments on a gas washing flask containing isopropanol. Total organic carbon analysis, laser diffraction, UV-vis spectrophotometry and transmission electron microscopy measurements have shown that cigarette smoke contains a large number and content of compounds soluble in water and isopropanol, together with solid particles generated during combustion. In contrast, negligible presence of non-combustion related particles was detected in Heets aerosol samples. These facts, together with the higher amount of water soluble compounds and higher number of polyaromatic hydrocarbons detected in the cigarettes smoke, allow to conclude that HTPs are less harmful than combusted cigarettes.

Highlights

Cigarette smoke has shown to be the cause of health problems like cardiovascular and chronic obstructive pulmonary diseases and lung cancer [1,2,3], and this has led to health authorities like the World Health Organization (WHO) [4,5] to promote measures to smoking cessation
Taking into account that the consumption time is 20% higher for ciga rettes than for Heets, total organic carbon content (TOC) analysis allows to considerer that, even using 20% more Heets, TOC content would be much higher in cigarettes samples
This difference would come from larger content of organic compounds, such as volatile organic compounds (VOCs), that can be partially dissolved in water

Summary

Introduction

Cigarette smoke has shown to be the cause of health problems like cardiovascular and chronic obstructive pulmonary diseases and lung cancer [1,2,3], and this has led to health authorities like the World Health Organization (WHO) [4,5] to promote measures to smoking cessation. With the purpose of reducing the inhalation of Harmful and Potentially Harmful Chemicals (HPHCs) [8,9,10], alternatives to regular cigarettes, like different tobacco and nicotine-containing products, such as elec tronic cigarettes, snus, or heated tobacco products (HTPs), have been developed. This approach intends to be an alternative for adult smokers who would otherwise continue smoking regular cigarettes. Delivery of nicotine and tobacco flavours by HTPs could help consumers to replace smoking cigarettes or to make a combined use of both systems [12,15, 16]

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