Abstract
plus adaptive plan 26 Gy resulted better dose volume histogram for all the organs at risks we evaluated than the original plan at 66 Gy, including V5, V10, V13,V15,V20, V25,V30 and the mean dose of total lung, V10, V20, V30, V40, V50, V60 and the mean dose of heart, V35, V40, V50, V55, V60, maximum dose and mean dose of esophagus (P<0.05), and the maximum dose of spinal-cord. Conclusion: PET-MTV may reduce significantly at the time of about 40 Gy during-RT and late course adaptive radiation therapy maybe an effective way to reduce the dose volume to the organs at risk in patients with NSCLC and deserve further study.
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