Comparison of osteoporosis in male smokers with or without COPD

Abstract

Background: We intended to investigate whether smoking and COPD is the independent risk factor of osteoporosis in male smoker in our population. Aims and Objectives: To see the frequency of osteoporosis in male smokers with and without COPD. Methods: This cross sectional comparative study was carried out in Sylhet Medical College Hospital, Bangladesh, during 01/07/2013 to 30/06/2015. 74 male smokers with COPD and 66 age-matched male smokers without COPD (control group) were consecutively enrolled. All individuals were underwent BMD by DEXA. Results: T-score (-2.31 ± 0.92 versus -1.65 ± 0.93; p<0.001) and BMD (0.77 ± 0.11 gm/Cm2 versus 0.86 ± 0.12 gm/Cm2; p<0.001) of the neck of femur were significantly lower in COPD group than that of control group (0.77 ± 0.11 gm/Cm2 versus 0.86 ± 0.12 gm/Cm2; p<0.001) . Similarly T-score (-3.01 ± 1.26 in COPD versus -1.92 ± 1.13; p Conclusions: The prevalence of osteoporosis in patients with COPD was higher than the age-matched control subjects without COPD. A lower FEV1 further increases the risk of osteoporosis in patients with COPD.