Abstract
Blood transfusion has an important role in patients undergoing surgery. However, besides providing sufficient amounts of oxygen, blood transfusion should protect the safety of blood recipients too. Hemoglobin (Hb) is the most abundant intra-erythrocytic protein and reacts rapidly with nitic oxide (NO), the endothelium-derived relaxing factor that maintains blood flow and oxygen transport to tissues. The interaction of NO and Hb have been found to have unavoidable consequences. Clinical factors play an important role in the decision of transfusion if otherwise avoidable. Keywords: Blood transfusion, Nitric oxide, Hemoglobin.
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