Comparison of neonatal outcomes of small for gestational age and appropriate for gestational age preterm infants born at 28–36 weeks of gestation: a multicentre study in Ethiopia

Netsanet Workneh Gidi,Bogale Worku,Orsolya Genzel-Boroviczeny,Elizabeth Mcclure,Assaye K Nigussie,Lulu M Muhe,Robert L Goldenberg,Matthias Siebeck,Amha Mekasha

doi:10.1136/bmjpo-2020-000740

Abstract

PurposeThe aim of this study was to assess morbidity and mortality pattern of small for gestational age (SGA) preterm infants in comparison to appropriate for gestational age (AGA) preterm infants...

Highlights

Intrauterine growth restriction (IUGR) occurs in about 24% of newborns per year, and the majority are born in low-income and middle-income countries (LMICs).[1]
►► Accelerated maturity associated with intrauterine growth restriction expected in small for gestational age (SGA) preterm infants did not protect them from respiratory distress syndrome (RDS) and mortality
Other obstetric factors studied such as premature rupture of membranes (PROM), antepartum haemorrhage and chorioamnionitis were more common in mothers of appropriate for gestational age (AGA) preterm infants (p

Summary

Introduction

Intrauterine growth restriction (IUGR) occurs in about 24% of newborns per year, and the majority are born in low-income and middle-income countries (LMICs).[1] IUGR is one of the rising public health challenges, because it contributes to increased risk of neonatal morbidity and mortality, and. ►► Intrauterine growth restriction is one of the common perinatal complications associated with increased neonatal morbidity and mortality. ►► This results in acceleration of brain and lung maturation, several studies have reported contradictory findings on the morbidity and mortality patterns of small for gestational age (SGA) infants. ►► Accelerated maturity associated with intrauterine growth restriction expected in SGA preterm infants did not protect them from RDS and mortality.

Objectives

Methods

Findings

Discussion

Conclusion