Abstract
The aim of the study was to compare simultaneously recorded a NIR-T/BSS and NIRS signals from healthy volunteers. NIR-T/BSS is a device which give an ability to non-invasively detect and monitor changes in the subarachnoid space width (SAS). Experiments were performed on a group of 30 healthy volunteers (28 males and 2 females, age 30.8 ± 13.4 years, BMI = 24.5 ± 2.3 kg/m2). We analysed recorded signals using analysis methods based on wavelet transform (WT) for the wide frequency range from 0.0095 to 2 Hz. Despite the fact that both devices use a similar radiation source both signals are distinct from each other. We found statistically significant differences for WT amplitude spectra between both signals. Additionally, we showed different relationships of both signals to blood pressure. Collectively, based on the present findings and those of previous studies, we can conclude that the combination of NIR-T/BSS or NIRS signals and time–frequency analysis opens new frontiers in science, and give possibility to understand and diagnosis of various neurodegenerative and ageing related diseases to improve diagnostic procedures and patient prognosis.
Highlights
The aim of the study was to compare simultaneously recorded a NIR-T/BSS and near-infrared spectroscopy (NIRS) signals from healthy volunteers
It is evident that subarachnoid space width (SAS) and HbO2 signals (Fig. 1b,c) have more low frequency components than the blood pressure (BP) signal (Fig. 1a)
This study investigated the relationship between the NIR-T/BSS and NIRS signals
Summary
The aim of the study was to compare simultaneously recorded a NIR-T/BSS and NIRS signals from healthy volunteers. NIR-T/BSS is a device which give an ability to non-invasively detect and monitor changes in the subarachnoid space width (SAS). The ability to non-invasively detect and monitor changes in the subarachnoid space width (SAS), which begin to address perfusion pressure and cerebrospinal fluid pulsatility, has been developed[2,3,4]. Monte Carlo simulations were performed to illustrate that for the chosen source-detector d istances[11], the dominant contribution of the NIR-T/BSS signal is SAS width changes rather than the absorption of the brain. Frydrychowski et al.[12] showed high interdependence (r = 0.81, p < 0.001) between NIR-T/BSS signal and SAS width changes measured with magnetic resonance imaging. The local oxygen saturation of the haemoglobin measured absorption can be used
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