Abstract
Coronary artery disease is one of the most common and important health problems in the world. Early diagnosis of this disease is very important to treat before severe myocardial damage occurred. Myocardial perfusion scintigraphy (MPS) and computed tomography coronary angiography (CTCA) which evaluates regional myocardial perfusion and coronary arteries, respectively, are reliable and non-invasive methods in terms of coronary artery disease. In this study we aimed to compare MPS and CTCA based on conventional coronary angiography (CCA). Totally 60 patients were included in the study. CCA and MPS were performed to 30 patients; CCA and CTCA were performed to the rest of the patients (30 patients). Lesions were classified as mild, moderate and severe in these imaging methods. MPS and CTCA were compared with CCA by using chi-square and Fisher’s exact test. MPS and CTCA’s p values were found for left anterior descending artery (LAD) p: 0, p: 0.271; for circumflex artery (Cx) p: 0.256, p: 0.08 and for right coronary artery (RCA) p: 0.033, p: 0.271, respectively. Furthermore MPS and CTCA’s sensitivity, specificity, accuracy, positive predictive value and negative predictive value were calculated 81% to 87%; 70% to 49%; 73% to 72%; 54% to 72%; 90% to 71%, respectively. CCA results were found more concordant with MPS for LAD and RCA lesions and more concordant with CTCA for Cx lesions. It was also found that positive predictive value of MPS and negative predictive value of CTCA were significantly higher than the others. As a result, MPS and CTCA were suggested as complementary techniques for the diagnosis of coronary artery disease, not as alternatives to each other.
Highlights
Coronary artery disease is the most common and one of the most important health problems
Our aim in this study is to evaluate Myocardial perfusion scintigraphy (MPS) and computed tomography coronary angiography (CTCA), comparing with conventional coronary angiography (CCA), which is the gold standard method for diagnosis of coronary artery disease, and to compare the efficacy of these two different imaging methods in the diagnosis of coronary artery disease
60 patients who were followed with the suspicion of coronary artery disease were included in this study. 30 patients with positive MPS and/or severe cardiac symptoms and other 30 patients who have positive CTCA and/or severe cardiac symptoms underwent coronary angiography
Summary
Coronary artery disease is the most common and one of the most important health problems. It is the obstruction of the coronary arteries feeding the heart muscle because of the hardening of the arteries which is called atherosclerosis. Early diagnosis of this disease is very important in terms of the treatment without severe myocardial injury. History of the patient is very important in the coronary artery diseases as the other diseases. The majority of patients refers to the doctor with chest pain. The cause of chest pain is a subjective criteria, as well as may be cardiac or non-cardiac causes. The cause of chest pain has to be exactly determined whether if it is cardiac origin or not
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