Comparison of Muscle Volume Between Congenital and Acquired Superior Oblique Palsies by Magnetic Resonance Imaging

Abstract

Magnetic resonance imaging (MRI) studies of superior oblique (SO) muscles have revealed a high incidence of SO muscle atrophy/hypoplasia in congenital SO palsy patients. It has also been reported that long-standing acquired SO palsy patients show atrophic SO muscles in the affected eye. The purpose of this study was to compare the incidence of SO muscle atrophy/hypoplasia in congenital and acquired SO palsy by utilizing MRI. Coronal MRI image planes were taken from 29 cases of unilateral congenital SO palsy and 9 cases of acquired unilateral SO palsy patients. The SO muscle bellies were traced and their sizes were measured from each image plane. The total volume of the affected superior oblique muscle was compared with that of the normal fellow eye. The mean volume of the affected superior oblique muscle to that of the normal muscle was 45.3% (SD = 30.1) in the congenital group and 65.8% (SD = 22.7) in the acquired group. The volume reduction of the SO muscle in congenital SO palsy patients appears to be mainly a congenital abnormality rather than a secondary change, as seen in acquired SO palsy patients.