Abstract

Brain Magnetic Resonance Imaging (MRI) has become a widely used modality because it produces multispectral image sequences that provide information of free water, proteinaceous fluid, soft tissue and other tissues with a variety of contrast. The abundance fractions of tissue signatures provided by multispectral images can be very useful for medical diagnosis compared to other modalities. Multiple Sclerosis (MS) is thought to be a disease in which the patient immune system damages the isolating layer of myelin around the nerve fibers. This nerve damage is visible in Magnetic Resonance (MR) scans of the brain. Manual segmentation is extremely time-consuming and tedious. Therefore, fully automated MS detection methods are being developed which can classify large amounts of MR data, and do not suffer from inter observer variability. In this paper we use standard fuzzy c-means algorithm (FCM) for multi-spectral images to segment patient MRI data. Geodesic Active Contours of Caselles level set is another method we implement to do the brain image segmentation jobs. And then we implement anther modified Fuzzy C-Means algorithm, where we call Bias-Corrected FCM as BCFCM, for bias field estimation for the same thing. Experimental results show the success of all these intelligent techniques for brain medical image segmentation.

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