Comparison of Mindfulness-Based Cognitive Therapy (MBCT) with Acceptance and Commitment Therapy (ACT) On the Severity of Fatigue, Improvement of Sleep Quality and Resilience in a Patient with Prostate Cancer: A Single-Case Experimental Study

Abstract

Introduction: Fatigue, loss of sleep quality and resiliency are considered as some of the complications of androgen deprivation therapy (ADT) in metastatic prostate cancer. Third-wave therapies of psychology mainly help to increase well-being through expanded resilience. The present study aimed to comparing the effectiveness of mindfulness-based cognitive therapy (MBCT) with acceptance and commitment therapy (ACT) on severity of fatigue, sleep quality and the resiliency in a patient with prostate cancer. Case Presentation: A 64-year-old man with localized prostate carcinoma was selected among respondent-driven sampling (RDS). He was treated with methadone after radical prostatectomy and was receiving the treatment for androgen deprivation therapy. After two 3-week baselines he received MBCT and ACT for three weeks. This A1B1C1A2B2C2 reversed design was along with a multiple baseline and a 6-month follow-up (during February to September 2015). The data were analyzed by means of a generalized estimation equation (GEE) and repeated measures correlation (rmcorr). The primary outcomes showed that both MBCT and ACT were effective on fatigue severity, sleep quality and resiliency (P 0.01). Secondary outcomes showed that there is an inverse relationship between the severity of fatigue, sleep quality and the resiliency (P < 0.01). Conclusions: The findings of this study, consistent with the research background, suggested the effectiveness of third wave interventions in the improvement of psychological indices in patients with cancer.