Comparison of Male and Female Breast Cancer Incidence and Mortality Trends in Central Serbia

Sandra Sipetic-Grujicic,Isidora Ratkov,Jelena Marinkovic,Milan Bjekic,Dragan Miljus,Zafir Murtezani,Anita Grgurevic

doi:10.7314/apjcp.2013.14.10.5681

Sandra Sipetic-Grujicic, Isidora Ratkov + Show 5 more

Open Access

https://doi.org/10.7314/apjcp.2013.14.10.5681

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Abstract

To compare breast cancer incidence and mortality trends in Central Serbia between males and females in the period 1999-2009. In this descriptive study, mortality data were obtained from the National Statistics Institute and morbidity data were derived from Institute of Public Health of Serbia for the period of interest. Breast cancer is a leading cancer in the female population of Central Serbia, whereas in male population it is not on the list of 10 leading localizations, concerning both incidence as well as mortality. In the period 1999-2009 the average standardized incidence rates of breast cancer were 60.5/100,000 in women and 1.4/100,000 in men, while average standardized mortality rates were 20.4/100,000 and 0.4/100,000. The average standardized incidence and mortality rates were about 45 times higher in females than males. Male breast cancer comprises approximately 2.1% of all breast cancer cases. The average age-specific mortality and incidence rates increased with age in both sexes. In the observed period standardized mortality rates of breast cancer increased significantly only in men (y=0.320+0.021?, p=0.044). The increase of breast cancer incidence in both sexes and mortality in men, indicate an urgent need for Serbian health professionals to apply existing cancer control and preventive measures. Male breast cancer is more present than in other world regions, with an outstanding increase of mortality, which demands a timely identification (screening) and adequate treatment. A national policy including mammography should be considered in the light of the newest findings.

Highlights

Breast cancer is the most commonly diagnosed cancer in women worldwide
The highest rates of breast cancer incidence are noted in North America, North and West Europe and Australia (American Cancer Society, 2011)
The source of mortality data (1999-2009) related to the male and female breast cancer and all malignant tumors were obtained from The National Statistics Institute for the period 1999-2009

Summary

Introduction

Breast cancer is the most commonly diagnosed cancer in women worldwide. It is estimated that there were 1,4 million of new cases in 2008, that comprises 23% of all cancers in female population and 10.9% of all cancers which ranks it on the second place, just behind lung cancer (1.6 million of new cases comprises 12.7% of all cancers) (Ferlay et al, 2010: http://globocan.iarc.fr./). Starting with 1999, the rates of breast cancer incidence have decreased in The USA, Canada and in countries of West and North Europe, whereas they have risen in many Eastern European, African, Latin American and Asian countries (Jemal et al, 2010). In the overall structure of dying from malign tumors in the world, breast cancer is on the fifth place behind lung, gastric, liver cancer and colorectal carcinoma, but it is first ranked when only female population is being observed (Ferlay et al, 2010: http://globocan.iarc.fr./). To compare breast cancer incidence and mortality trends in Central Serbia between males and females in the period 1999-2009. In the observed period standardized mortality rates of breast cancer increased significantly only in men (y=0.320+0.0215, p=0.044). A national policy including mammography should be considered in the light of the newest findings

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Conclusion