Abstract
(Anesth Analg. 2021;132:1626–1634) Postoperative pain can negatively affect patient satisfaction and is associated with increased risk of complications as well as increased opioid use. Regional anesthesia can reduce postoperative pain and opioid use, but there are limitations to current techniques. Single-injection regional anesthesia has limited duration of analgesic effects, while continuous catheter infusions are more challenging and require greater resources. Liposomal bupivacaine wound infiltration has been shown to prolong analgesic effects and reduce the use of opioids. This systematic review considers recent studies on the use of liposomal bupivacaine compared to local anesthetics in regional anesthesia.
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