Abstract
BackgroundHeartMate II (HM II) and HeartWare (HW) Left Ventricular Assist Devices have been successfully used in end-stage heart failure patients as a bridge to transplantation, recovery, or decision. We set out to compare their effect in off-loading the left ventricle and its geometry.MethodsThe left ventricular end diastolic (LVEDD) and end systolic (LVESD) diameters were compared between first time HM II (n = 25) and HW implantations (n = 24) before and after the operation at 1, 3, and 6 months. A p value of less than 0.05 was considered as significant.ResultsPost-operative LVEDD and LVESD at 1, 3, and 6 months were significantly reduced in comparison with pre-operative values in both HM II and HW groups. No significant difference was found comparing HM II and HW groups together before and after the operation.ConclusionsOur study shows that both HM II and HW can significantly reduce the left ventricular systolic and diastolic dimensions and off-load the left ventricle. The miniaturized nature of HW does not affect its performance and it could be as effective as HM II.
Highlights
HeartMate II (HM II) and HeartWare (HW) Left Ventricular Assist Devices have been successfully used in end-stage heart failure patients as a bridge to transplantation, recovery, or decision
There has been a debate if the miniaturized nature of the pump could affect its effect on off-loading of the left ventricle, in comparison with the bigger second generation Ventricular Assist Devices (VAD) systems
Echocardiography data is inclusive of the left ventricular systolic diameter and the left ventricular diastolic diameter at baseline VAD pump speed (9600 rpm for HM II and 2800 rpm for HW)
Summary
HeartMate II (HM II) and HeartWare (HW) Left Ventricular Assist Devices have been successfully used in end-stage heart failure patients as a bridge to transplantation, recovery, or decision. The smaller second generation continuous-flow assist devices have successfully replaced their first generation pulsatile predecessors. They have proved to be more reliable, smaller in size, and have. Another recent addition to this family is HeartWare VAD (HeartWare Inc). There has been a debate if the miniaturized nature of the pump could affect its effect on off-loading of the left ventricle, in comparison with the bigger second generation VAD systems. We set out to compare the effect of HeartWare (HW) and Number Male
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