Abstract

Aims. The objective of this preliminary study was to specifically compare sentinel lymph nodes (SLNs) detection rates obtainable by injecting blue dye or radioactive tracer in women with endometrial cancer undergoing laparoscopic staging. Methods. Seven patients with early stage endometrial cancer were enrolled. The assessment of SLNs was done laparoscopically. The radioactive tracer was injected into the cervix 24 hours before surgery. Blue dye was injected into the cervix the day of surgery. Radioactive SLNs were identified with a gamma-scintiprobe. Both SLNs and non-SLNs were evaluated for micrometastases. Results. The SLNs detection rate was 100% for the radioactive tracer and 71% for blue dye. All the four patients (100%) with lymph node metastases had SLNs identified by the radioactive tracer whereas only two (50%) had SLNs identified by blue dye. Conclusions. Radioactive tracer seems to be more reliable to predict lymph node status in women with endometrial cancer undergoing laparoscopic staging

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