Comparison of Laboratory Values of Prisoner and Civil Patients with Chronic Hepatitis B

Abstract

OZET Objective: Since immune processes play a role in the pathogenesis of HBV infection, the immune system of the host is an important factor in the healing of the infection. The aim of the present study is to compare the laboratory findings related to hepatitis B in inmates with chronic hepatitis B, who live in a confined space and whose immune system is affected by various stress factors, and civilian chronic hepatitis B patients. Materials and Methods: The approval of the Dicle University Medical School, NonInvasive Clinical Studies Ethics Committee was obtained for the study. Inmates and civilians with hepatitis B who presented to the infectious diseases outpatient clinic between December 2010 and June 2013 were enrolled in the study. Both groups were statistically compared in terms of HBV DNA, ALT, AST and HBeAg. Results: A total of 34 inmates and 34 civilian patients were evaluated. While no difference was observed in terms of the liver enzymes, HBeAg positivity was significantly higher among the inmates. Also, a HBV DNA > 104 copies/ml was more frequently observe din the group of inmates, although the difference was statistically insignificant. Conclusion: Studies comparing chronic hepatitis B patients who are leading different lifestyles will help select the patients with priority for treatment. (Viral Hepatitis Journal 2014; 20(2): 57-60)