Abstract
Intravenous procainamide hydrochloride has prognostic value for drug efficacy in electrophysiologic testing in patients with sustained ventricular tachycardia 1,2 and is often used as an initial screen for drug therapy in these patients. To evaluate the effects of varying intravenous procainamide dosing regimens on providing stable plasma concentrations of the drug in the clinical electrophysiology laboratory, we compared procainamide dosing and maintenance infusions determined by population kinetics 3 with those of a standard fixed dose and maintenance infusion. 2
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