Abstract
ObjectiveThe objective of this study was to compare three analgesic protocols for feline castration. Study designProspective, randomized clinical study. AnimalsForty-nine client-owned cats. MethodsCats were injected with intramuscular (IM) dexmedetomidine (15 μg kg−1) and alfaxalone (3 mg kg−1) and assigned randomly to one of three treatment groups. Group ITL (n = 15) were administered intratesticular 2% lidocaine (0.05 mL each testicle), group SCL (n = 15) a sacrococcygeal epidural injection of 2% lidocaine (0.1 mL kg−1) and group IVM (n = 19) intravenous (IV) methadone (0.3 mg kg−1), before surgery. Cardiorespiratory variables were recorded. In case of autonomic nociceptive response, IV fentanyl (2 μg kg−1) was administered. During recovery, time from IM atipamezole (75 μg kg−1, administered at the end of surgery) to sternal recumbency and to active interaction was recorded. Quality of recovery was assessed using a simple descriptive scale. Postoperative analgesia was evaluated using a visual analogue scale and the UNESP-Botucatu multidimensional composite pain scale (MCPS) at return of active interaction and then 1, 2 and 3 hours later. ResultsThe three analgesic protocols were comparable in terms of intraoperative fentanyl and propofol requirement. Cardiorespiratory variables stayed within normal ranges in the majority of the cases, although group IVM had the lowest intraoperative respiratory rate (p = 0.0009). No differences were detected between groups in UNESP-Botucatu MCPS scores (p = 0.21). However, group ITL showed higher visual analogue scale score than group IVM (p = 0.001). Four cats enrolled in group ITL, as well as three of group SCL and one of group IVM, required rescue analgesics before the completion of pain assessment. Conclusions and clinical relevanceIntratesticular and sacrococcygeal epidural lidocaine injections could be regarded as good alternatives to systemic opioids in cats undergoing castration, although the benefits of these techniques seem to be of shorter duration than IV methadone.
Highlights
Neutering of client-owned cats is a common procedure in veterinary practice
Postoperative analgesia was evaluated with a visual analogue scale (VAS) and the UNESP-Botucatu multidimensional composite pain scale (MCPS)
Cardiorespiratory variables stayed within normal ranges in the majority of the cases, group IVM had the lowest intraoperative respiratory rate (p = 0.0009)
Summary
When performing castration of male cats the majority of French veterinarians prefer injectable anaesthetic techniques to inhalation anaesthesia. The reasons behind this choice may be a lack of familiarity with feline tracheal intubation, as well as the potential for complications associated with this procedure (Brodbelt et al 2007). An intramuscular (IM) anaesthetic protocol for castration should be safe for the animal, inexpensive, and provide reliable unconsciousness, muscle relaxation and analgesia. Combinations of alpha 2-adrenoreceptor agonists, induction agents suitable for IM administration and opioids are used for this purpose (Adami et al 2015). Systemic full μ-opioid agonists are commonly employed to provide perioperative analgesia
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