Abstract
To compare the measurement of flap thickness using intraoperative ultrasound pachymetry and postoperative Visante anterior segment optical coherence tomography (Visante-OCT) in eyes receiving laser in situ keratomileusis (LASIK). Seventeen patients (34 eyes) received LASIK using a Technolas-217Z100 laser and AMADEUSⅡ mechanical microkeratome (140μm head). Flap thickness was assessed with an ultrasound pachymeter intraoperatively and a Visante -OCT postoperatively at 1 week and 1 month. The intraoperative mean flap thickness by ultrasound pachymetry was (124±13.9) μm (range: 96.5 to 160 μm), and mean flap thickness by Visante-OCT was (145±7.13) μm (range: 130 to 158 μm) and (143±5.32) μm (range: 132 to 155 μm) postoperatively at 1 week and 1 month respectively (F =63.52, P<0.01). Intraoperative subtraction pachymetry underestimated flap thickness compared with postoperative Visante-OCT (P<0.01). There was no significant difference between postoperative Visante-OCT measurements at 1 week and 1 month after LASIK (P=0.16). The 95% limit of agreement (LoA) of flap thickness between ultrasound Visante-OCT and pachymetry was -5.40 to 42.10 μm. OCT overestimates flap thickness compared with intraoperative ultrasound pachymetry when using the AMADEUSⅡ mechanical microkeratome.
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