Comparison of intranasal and intratracheal oxygen administration in healthy awake dogs

Abstract

Summary Intranasal (in) and intratracheal (it) oxygen administration techniques were compared by measuring inspired oxygen concentrations () and partial pressures of arterial oxygen () in 5 healthy dogs at various in (50, 100, 150, and 200 ml/kg of body weight/min) and it (10, 25, 50, 100, 150, 200, and 250 ml/kg/min) oxygen flow rates. Intratracheal administration of oxygen permitted lower oxygen flow rates than in administration. Each it oxygen flow rate produced significantly higher and than the corresponding in flow rate. An it oxygen flow rate of 25 ml/kg/min produced and values equivalent to those produced by an in oxygen flow rate of 50 ml/kg/min. An it oxygen flow rate of 50 ml/kg/min produced and values equivalent to those produced by in oxygen flow rates of 100 and 150 ml/kg/min. All it oxygen flow rates ≥ 100 ml/kg/min produced and values that were greater than and values produced by in oxygen flow rates of 200 ml/kg/ min. The lowest flow rates studied (50 ml/kg/min, in, and 10 ml/kg/min, it) produced capable of maintaining 97% hemoglobin saturation, which should be adequate for most clinical situations. Arterial blood gas analysis and measurements are necessary to accurately guide oxygen flow adjustments to achieve the desired and to prevent oxygen toxicity produced by excessive .