Comparison of Intracytoplasmic Sperm Injection Outcomes in Patients With Cryptozoospermia and Severe Oligozoospermia

Abstract

To evaluate the intracytoplasmic sperm injection (ICSI) outcomes in patients with cryptozoospermia and severe oligozoospermia. A retrospective study. Three hundred sixty severe oligozoospermic patients were attended ICSI cycles from January 2004 to December 2004. Patients were divided in to 3 groups according to the sperm concentration: Group I 1-≤5 X 106/ml, Group II <1 X106/ml, Group III spermatozoa were presented in the pellet (cryptozoospermia). The fertilization (2PN/injected), clinical pregnancy (sac presence in the ultrasound), and implantation rate (sacs/embryos transferred) were evaluated in ICSI cycles using ejaculated sperm. In all groups, female age was under 38 years and more than 3 oocytes were available for injection. In the cryptozoospermic patients (Group III) fertilization, pregnancy and implantation rates were lower compare to Group I and II. However, statistical analysis did not show any significance between fertilization, pregnancy and implantation rates of those groups (Table). Tabled 1 ICSI is an effective treatment in severe oligozoospermic patients. Our data showed that the fertilization, pregnancy, and implantation rates were increasing with the higher sperm concentration in patients with severe oligozoospermia. However, the ICSI results in cyptozoospermic patients were comparable with severe oligozoospermic patients.