Comparison of Intra Operative Cytology and Frozen Section with Permanent Pathologic Results in Ovarian Masses

Abstract

Objectives: Making a decision on the extent of surgery for ovarian tumors depends on the intraoperative diagnosis. The aim of this study was to compare the intraoperative cytology and frozen section (FS) for diagnosis of ovarian masses. Materials and Methods: One hundred and thirty-one patients with ovarian masses who underwent surgery for ovarian neoplasms were evaluated by intraoperative scrape and FS techniques and compared to final pathologic diagnoses. Results: Scrape cytology for intraoperative diagnosis of benign ovarian tumors had sensitivity of 89.06% compared to 90.62% for FS. Specificity of both scrape and FS techniques for benign tumors was 94.91%. Sensitivity and specificity of scrape for malignant ovarian tumors were 94.91% and 89.06%, respectively. The related values for FS were 94.91% and 90.62%. The overall accuracy percentage of scrape and FS for diagnosis of ovarian neoplasms was 91.86% and 92.68%, respectively. Conclusion: Intraoperative scrape cytology has high accuracy in diagnosis of ovarian tumors and is comparable with FS.