Comparison of Hypofractionated and Conventional Preoperative Radiotherapy for Locally Advanced Rectal Cancer in the Elderly

Abstract

Neoadjuvant chemoradiotherapy is considered as the standard approach for T3-4 M0 rectal cancer, despite that the optimal dose fractionation remains undefined in the elderly. We performed a retrospective analysis in order to compare conventional (C) and hypofractionated (HF) schedule in elderly patients, in terms of survival and morbidity.