Comparison of Hydrocolloid Dressings and Silver Nanoparticles in Treatment of Pressure Ulcers in Patients with Spinal Cord Injuries: A Randomized Clinical Trial.

Parvaneh Asgari,Amir Hossien Abdi,Fatemeh Bahramnezhad,Yee Bit-Lian,Younes Mohammadi,Mitra Zolfaghari

doi:10.34172/jcs.2022.08

Abstract

Introduction: There are numerous dressings used to treat pressure ulcers (PUs), depending on their advantages to achieve optimum patient outcomes. This study aimed to compare hydrocolloid dressings and silver nanoparticles in treating PUs among patients with spinal cord injury (SCI). Methods: This randomized clinical trial was conducted on 70 patients with SCI in Iran. Participants were randomly divided into two equal groups (n=35) receiving silver nanoparticle dressing and hydrocolloid dressing, respectively. The groups were evaluated in four assessment periods using the Bates-Jensen Wound Assessment Tool (BWAT). Data analysis was performed using SPSS software version 13, repeated measures ANOVA, non-parametric tests, and chi-square. Results: Chi-square test was used to investigate the difference between the scores before the intervention, the results of which were not statistically significant. In repetitive measurements, the results of the analysis of variance showed that the average assessment score in both groups decreased and both dressings were effective in the treatment process. Although PU improvement status in the group that received silver nanoparticles was better, between-group analysis of variance did not show any statistically significant difference between the two groups. Conclusion: Our results indicated that silver nanoparticles and hydrocolloid dressings can be used interchangeably in the treatment of PUs.

Highlights

There are numerous dressings used to treat pressure ulcers (PUs), depending on their advantages to achieve optimum patient outcomes
To determine the required sample volume at 95% confidence level and 80% power, it was assumed that the hydrocolloid dressing in comparison with silver nanoparticles can reduce the average wound surface by 10% in the process of healing PUs in comparison with the control group
The findings of this study showed that the mean (SD) of age in patients receiving silver nanoparticle and hydrocolloid groups was 69.5 (14.58), 69.08 (16.2), respectively

Summary

Introduction

There are numerous dressings used to treat pressure ulcers (PUs), depending on their advantages to achieve optimum patient outcomes. This study aimed to compare hydrocolloid dressings and silver nanoparticles in treating PUs among patients with spinal cord injury (SCI). 33% of patients with SCI experience PU at least after one year.[4] These patients, due to the relatively incomplete ability to move, urinary and stool incontinence, and malnutrition are more sensitive against PU and the wound healing process in these people is very slow.[5]. Some drugs such as antipsychotics, muscle relaxants, analgesics, and blood flow-modifying drugs can be effective in treating ulcers.[6]

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Discussion

Conclusion