Abstract
Introduction and purposeThis article aims to compare two guiding methods of cervical cancer screening: cervical cytology and HPV testing. The objective is to provide information on which method is currently more relevant in the early detection of precancerous lesions. 
 Material and methodThis review was mainly based on articles collected in Pubmed i years 2015-2022. The research was done by looking through keywords as follows: “cervical cancer”, “cytology”, “HPV testing”.
 ResultsAll selected studies have demonstrated that HPV testing is a more appropriate indicator for initial high-grade CIN (cervical intraepithelial neoplasia) than cytology.
 ConclusionsAccording to the cited researches, the public health system should definitely pay more attention to HPV testing as the first stage of cervical cancer screening. Moreover, it should clarify by comparing all advantages and disadvantages of methods, which further diagnostic pathway is the most effective and has the best outcomes for the patients. 
 Keywordscervical cancer, cervical screening, cytology, HPV primary screening, HPV testing
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