Abstract

This paper reports on a head-to-head study of howRU and EQ-5D on patients with cardiovascular disease. howRU is a short generic measure of health-related quality of life comprising 39 words, designed for routine use, which we compare with EQ-5D (230 words). Patients attending a clinic completed both instruments. Completed data were available for 116 patients, 51% female, mean age 56 and SD 20. howRU is shorter, has better readability statistics, a higher completion rate, a wider range of states used and a smaller ceiling effect than EQ-5D. The correlations of howRU with EQ-5D are similar to those of EQ-5D with other validated instruments.

Highlights

  • Measures of health-related quality of life (HRQoL), known as patient-reported outcome measures (PROMs), were developed originally for population health surveys, ­economic ­evaluation of new medicines and resource allocation

  • PROMs form an overarching indicator in the National Health Service (NHS) outcome framework,[2] reinforcing the NHS’ intention to move away from focusing on activity and process targets to measuring outcomes as perceived by patients

  • EQ-5D is a standardised generic self-completion measure of health status, originally developed for clinical and economic appraisal and population surveys, and in particular to support the calculation of quality-adjusted life years (QALYs) in costutility analysis.[5]

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Summary

Background

Measures of health-related quality of life (HRQoL), known as patient-reported outcome measures (PROMs), were developed originally for population health surveys, ­economic ­evaluation of new medicines and resource allocation. EQ-5D is a standardised generic self-completion measure of health status, originally developed for clinical and economic appraisal and population surveys, and in particular to support the calculation of quality-adjusted life years (QALYs) in costutility analysis.[5] EQ-5D has been used in the NHS PROMs programme for hip and knee replacement, groin hernia and varicose vein operations. The EQ-5D descriptive system has five dimensions (mobility, self-care, usual activities, pain/discomfort and anxiety/­ depression), each with three response options, typically (1) none/absent, (2) moderate/some and (3) unable/extreme, creating 243 (35) possible states.

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