Comparison of Hemodynamic, Emergence and Recov Ery Characteristics of Sevoflurane with Desflurane in General Anesthesia

Abstract

General anesthesia is a dynamic balance between the level of hypnosis, analgesia, and stimulation. It is usually defined as a triad of amnesia, analgesia, and muscle relaxation. Inhaled volatile anaesthetics remain the most widely used drugs for maintenance of general anesthesia because of their predictable intraoperative and recovery characteristics. Management of haemodynamic stability and early recovery is the most important part of a standardized balanced technique. The aim of this study is to prospectively compare the hemodynamic, emergence and recovery characteristics of sevoflurane with that of desflurane in general anesthesia. 60 ASA I and II patients undergoing elective surgical procedures less than 3 hours duration under endotracheal general anesthesia were randomly divided into two groups. Both the groups were induced with standard intravenous induction technique. Group D was maintained with 3% desflurane and group S with 1% sevoflurane in 50% oxygen with 50% nitrous oxide. In conclusion, desflurane provides earlier emergence and recovery from anesthesia compared to sevoflurane. Both desflurane and sevoflurane maintained hemodynamic stability intraoperatively, but to maintain the hemodynamicsdesflurane needed more number of additional doses of fentanyl.