Abstract

Background Post-processing methods have been developed to quantify myocardial strain from steady-state free-precession (SSFP) cine images. In the left ventricle (LV), global strain measurements from SSFP in healthy volunteers and in some types of heart disease compare favorably with myocardial tagging as a reference. We compared heart deformation analysis (HDA) of SSFP images and cine Displacement Encoding with Stimulated Echoes (DENSE) for the assessment of global and segmental circumferential strain (Ecc) and derivative indices in healthy volunteers and heart failure (HF) patients with left bundle branch block (LBBB).

Highlights

  • Post-processing methods have been developed to quantify myocardial strain from steady-state free-precession (SSFP) cine images

  • Imaging was performed on a 1.5T Siemens Avanto MR system in 3 short-axis planes in 6 volunteers and 29 patients with heart failure (HF)-left bundle branch block (LBBB)

  • Ecc was computed from SSFP images using heart deformation analysis (HDA) (Trufi Strain, Siemens Healthcare, Erlangen) and from cine Displacement Encoding with Stimulated Echoes (DENSE) using previously described methods[3,4]

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Summary

Introduction

Post-processing methods have been developed to quantify myocardial strain from steady-state free-precession (SSFP) cine images. In the left ventricle (LV), global strain measurements from SSFP in healthy volunteers[1,2] and in some types of heart disease compare favorably with myocardial tagging as a reference. We compared heart deformation analysis (HDA) of SSFP images and cine Displacement Encoding with Stimulated Echoes (DENSE) for the assessment of global and segmental circumferential strain (Ecc) and derivative indices in healthy volunteers and heart failure (HF) patients with left bundle branch block (LBBB)

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