Abstract

Introduction: Diabetes mellitus is a disorder characterized by hyperglycemia. It has been reported that 75% of the primary cause for mortality in diabetes mellitus patients is cardiovascular disease which is caused by hyperglycemia. Erythrocytes of diabetes mellitus patients have a shorter life span than normal. Red cell distribution width (RDW) is a measure of the heterogeneity of the volume of red blood cells (Red Blood Cells). High RDW has various adverse outcomes. The study aims to compare Haemoglobin, RDW and RBC values among diabetes mellitus and normal individuals.
 Materials and Methods: Blood samples of 20 patients with and without diabetes were collected from outpatients visiting Saveetha dental college and hospitals. The results of the following parameters Haemoglobin, RDW, RBC were analyzed using Independent t Test in SPSS software. The statistical significance (P value) was set at 0.05.
 Results: It is evident that there is a higher incidence of diabetes among the male population compared to females which result in higher RBC and Haemoglobin values. The RDW value is also reported to be higher in diabetic patients than non-diabetic patients. For Haemoglobin p value was 0.984 (>0.05), RDW p value was 0.180 (>0.05), RBC p value was 0.680 (>0.05). The p values were >0.05 which is statistically not significant.
 Conclusion: The Hemoglobin, RBC and RDW values are higher for diabetic patients than non-diabetic. Higher RDW has various adverse effects such as cardiovascular disease which may cause mortality in diabetes mellitus patients.

Highlights

  • Diabetes mellitus is a disorder characterized by hyperglycemia

  • The Hemoglobin, red blood cells (RBC) and Red cell distribution width (RDW) values are higher for diabetic patients than nondiabetic

  • Independent t test transpired with the p value of 0.18 (>0.05) which is statistically insignificant (Fig. 2)

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Summary

Introduction

The study aims to compare Haemoglobin, RDW and RBC values among diabetes mellitus and normal individuals. It has been reported that 75% of the primary cause for mortality in diabetes mellitus patients is cardiovascular disease which is caused by hyperglycemia [1]. Previous studies have demonstrated the associations between high RDW values and various adverse health outcomes [4]. The adverse outcomes of high RDW values are as follows: increased mortality, increased incidence of atrial fibrillation, heart failure, and adverse prognosis in patients with heart failure or coronary heart disease [5]. A correlation was demonstrated between RDW and low heart rate variability

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