Comparison of Guided Bone Regeneration using a Bovine Collagen Membrane vs a Calcium Sulfate Barrier

Abstract

ABSTRACTResorbable membranes have eliminated the need for re-entry for removal and reduce the incidence of adverse soft tissue reactions that accompany membrane exposure. However, the lack of rigidity often makes these more prone to collapse. Calcium sulfate has shown promise as a regenerative material alternative in a socket preservation application. The purpose of this study was to compare calcium sulfate and bovine collagen as a barrier in guided bone regeneration.Materials and MethodsEighteen sites were treated in this randomized, blinded clinical study. Patients were divided into 2 groups, 9 sites each. Group 1, had bovine collagen membrane (OssixTM) and group 2 had calcium sulfate barrier (CalcigenOralTM) to cover the graft. All sites were augmented with autogenously bone and demineralized freeze-dried bone composite graft at 1:1 ratio. Implants were placed in the grafted area 4 to 6 months post grafting. Vertical and horizontal ridge measurements were made before and after grafting by two blinded examiners.ResultsThe collagen membrane group had a mean bone gain of 1.06 ± 1.01 mm in width and 0.19 ± 1.11 mm in height. In comparison, the calcium sulfate group had a mean bone loss of –0.14 ± 0.74 mm in width and –0.19 ± 0.74 mm in height. Student t-test revealed a significant difference in width dimension between the two groups, p = 0.01.ConclusionOverall results of this study suggest that calcium sulfate might have limited use as barrier for ridge augmentation.How to cite this articleGhaly M, Kerns DG, Hallmon WW, Solomon ES, Nagy WW, Al-Hashimi I, Rossmann JA. Comparison of Guided Bone Regeneration using a Bovine Collagen Membranevsa Calcium Sulfate Barrier. J Contemp Dent 2013;3(3):138-143.