Comparison of Growth Parameters, Apgar score, the Blood Zinc, Magnesium, Calcium and Phosphor between Gestational Diabetic and Non-Gestational Diabetic Pregnant Women: a Prospective Cohort Study

Abstract

Background: Due to little attention to the combined effect of diabetes and pregnancy on mother an infants microelements in literatures. This study aimed to compare newborns growth parameters, Apgar score, the cord blood zinc, magnesium, calcium and phosphor between pregnant women with and without gestational diabetes mellitus. Materials and Methods: This prospective cohort study was conducted in Hamadan city, Iran, during 2013-14. Gestational diabetes considered as exposure and 20 women with gestational diabetes were individually matched with the 20 non-diabetic pregnant women in terms of the variables age, number of pregnancies, and type of delivery were included in this study. The cord blood and mother vein blood samples were taken immediately after delivery. Results: The mean of newborn's head circumference was 34.85±0.9 cm and 33.90±0.97 cm in mothers with gestational diabetes and non- diabetic mothers respectively (P<0.05). The mean of cord blood calcium was 9.81±0.6 mg/dl in the exposed group and 10.23±0.4 mg/dl in the control group (P<0.05) and these figures for zinc were 79.05±13.1 mg/dl in the exposed group and 86.96±11.6 mg/dl in the control group (P<0.05). Conclusion: This prospective cohort study showed the imbalance of some micronutrient in cord blood of mothers with gestational diabetes in comparison to non-diabetic mothers. Therefore in pregnant women with gestational diabetes should be more attention to be paid the concentrations of microelements.