Comparison of Garlic and Ginger Extract with Glibenclamide on Some Biochemical Standards in Diabetic Mice

Abstract

This study aimed to determine the effect of ethanolic extract of garlic (Allium sativum s.) and ginger on the levels of glucose, cholesterol, and triglycerides in the blood serum of adult white mice with induced diabetes. This study included 40 male mice of Balb/c, which were divided into four experimental groups (ten mice per group). The results showed a significant increase (p<0.05) in the concentration of glucose, cholesterol and triglycerides in the blood serum of the group of mice injected with alloxan compared with the physiological control. The results also showed a significant decrease (p<0.05) in the concentration of glucose, cholesterol and triglycerides in the blood serum of the group of mice treated with garlic and ginger extract compared to control glucose. Results showed that ethanolic extract of garlic (Allium sativum s.) and ginger has an important effect on lowering the level of biochemical to normal values equivalent to glibenclamide. KEYWORDS Alcoholic extract, alloxan, glucose, balb/c total cholesterol, triglycerides