Comparison of Functional Recovery Between Unicompartmental and Total Knee Arthroplasty: A Randomized Controlled Trial.

Abstract

Comparisons of functional recovery between unicompartmental knee arthroplasty (UKA) and total knee arthroplasty (TKA) using performance-based tests are lacking. Therefore, this study aimed to compare 2-minute walk test (2MWT) and Timed Up-and-Go test (TUG) results between UKA and TKA for isolated medial knee osteoarthritis (OA). We hypothesized that UKA yields faster functional recovery than TKA as measured with the 2MWT and TUG. We conducted a randomized controlled trial comparing medial UKA and TKA in patients with isolated medial knee OA. A total of 110 patients were enrolled; after 11 exclusions, 99 patients (50 UKA, 49 TKA) were included in the final analysis. The patients were tested using the 2MWT and TUG preoperatively and at 6 weeks, 3 and 6 months, and 1 and 2 years postoperatively. Patient-reported outcome measures (PROMs) were also evaluated. The mean 2MWT, TUG, and PROM results were compared between groups at each time point. The mean 2MWT distance after UKA was significantly longer than that after TKA at 6 weeks (96.5 ± 22.6 m for UKA compared with 81.1 ± 19.1 m for TKA; difference, 18 m [95% confidence interval (CI),10.4 to 25.6 m]; p < 0.001), 3 months (102.1± 24.4 compared with 87.5 ± 22.3 m; difference, 14.7 m [95% CI, 5.4 to 24.0 m]; p = 0.002), and 6 months (102.8 ± 16.2 compared with 89.6 ± 15.3 m; difference, 13.2 m [95% CI, 6.9 to 19.5 m]; p < 0.001). The values at 1 and 2 years were similar after UKA and TKA. The mean TUG after UKA was also significantly shorter than that after TKA at 6 weeks and 3 months. The mean PROMs were similar after both treatments, with the exception of the Oxford Knee Score and subscales of the Knee injury and Osteoarthritis Outcome Score at 6 weeks and 3 months postoperatively. The 2MWT indicated that UKA for isolated medial knee OA enabled faster recovery than TKA did at 6 weeks to 6 months, and earlier recovery was also seen with the TUG at 6 weeks to 3 months. The 2MWT and TUG results after UKA and TKA were similar to one another at 1 and 2 years. Therapeutic Level I. See Instructions for Authors for a complete description of levels of evidence.