Comparison of FP-7 and S2 Ahmed glaucoma valve implantation in refractory glaucoma

Abstract

Objective To compare the efficacy of using of FP-7 and S2 Ahmed glaucoma valve implantations (AGI) for refractory glaucoma and to monitor postoperative complications.Methods A retrospective study was conducted to document patients with refractory glaucoma who underwent S2 (26 eyes from 26 patients) or FP-7 (23 eyes from 23 patients) AGI in the Center Hospital of Cangzhou.The change in IOP,the surgical success rate,and postoperative complications were recorded and analyzed.A variance analysis of repeated measurement data was used for comparison of preoperative and postoperative IOP and the effect of reducing IOP in the 2 observation groups.Cumulative survival rates were calculated using survival analysis and compared using a log-rank.The Fisher exact test was used for the comparison of complication rates.Results IOP was reduced from 38.19±10.56 mmHg to 14.54±4.11,15.83±5.76,17.19±4.96,and 18.84±5.28 mmHg at month 1,month 6,month 12,and month 24 postoperatively in the S2 group and reduced from 39.91±9.12 mmHg to 14.41±5.14,15.95±4.32,17.11±4.75,and 19.06±6.55 mmHg in the FP-7 group.There was no statistically significant difference between the 2 groups for their effect on lowering IOP.At the last follow-up,the cumulative probabilities of success and of total success were 82％ and 74％ in the S2 group,and 80％ and 75％ in the FP-7 group.There was no statistically significant difference between the 2 groups.Conclusion FP-7 AGI was equal to S2 AGI in reducing IOP in refractory glaucoma.The complication rate in the S2 group was no higher than it was in the FP-7 group. Key words: Glaucoma drainage implant; Glaucoma; Intraocular pressure; Treatment outcome