Abstract
We have compared the results of four bilirubin binding tests performed simultaneously on blood samples collected from jaundiced newborn infants with serum bilirubin concentrations ranging from 7.3-34.4 mg/dl. Data from 176 blood samples were correlated using the Pearson (r) and Spearman(rho) correlation coefficients. Salicylate saturation index (SSI) correlated with the HBABA dye binding test (HABA)(r= -.16,rho= -.14, P<.05), the horseradish peroxidase apparent unbound bilirubin concentration (AUBC) (r=.45, rho= .48,P<.001), and the direct yellow fluorescent dye binding test (DY7) (r= -.43, rho= -.57, P<.001). Each test correlated significantly with the others using parametric and non-parametric methods. However,none of the bilirubin binding tests correlate well enough with another that one test could be used clinically to predict the value of the other.
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