Comparison of enteral and parenteral nutrition support therapy for patients in intensive care unit with critical diseases

Abstract

Objective To compare the clinical effects of enteral and parenteral nutrition support therapy for patients in intensive care unit(ICU) with critical diseases.Methods One hundred and fourteen patients with critical diseases were divided into enteral nutrition group and parenteral nutrition group by random digits table with 57 cases in each group.The hemoglobin,serum total protein,albumin,prealbumin and incidence of complications were compared.Results The levels of 4 indicators above in all patients after 2 weeks treatment were increased,in enteral nutrition group was significantly lower than that in parenteral nutrition group [hemoglobin:(120.47 ±22.46) g/L vs.(114.83 ±23.86) g/L,total protein:(78.21 ± 8.42) g/L vs.(70.48 ±8.21) g/L,albumin:(38.21 ±5.03) g/L vs.(33.87 ±5.62) g/L,prealbumin:(245.57 ±44.61) mg/L vs.(182.24 ±42.73) mg/L,P ＜0.05].The incidence of bloating and diarrhea,vomiting and nausea,infection,liver and kidney dysfunction in enteral nutrition group was significantly lower than that in parenteral nutrition group [14.04％ (8/57) vs.26.32％ (15/57),12.28％ (7/57) vs.17.54％ (10/57),3.51％(2/57) vs.8.77％(5/57),1.75％(1/57) vs.5.26％(3/57),P＜ 0.05].Conclusions Nutritional support is important for patients with critical diseases on nutritional status and immunity function,and the effect is more obvious of enteral nutrition,which can improve the prognosis greatly and may be a better nutrition support therapy. Key words: Parenteral nutrition; Enteral nutrition; Critical illness; Hemoglobin